Lần đầu tiên phát hiện được nhiều hợp chất mới có hoạt tính chống ung thư

<html> <head> <meta http-equiv='Content-Type' content='text/html; charset=utf-8'> <title> </title> </head> <div> <meta http-equiv="Content-Type" content="text/html; charset=utf-8"> <title></title> <div style="text-align: center; "><span style="font-size: small; "><span style="font-family: Arial; "><strong><span style="color: rgb(0, 0, 255); ">&nbsp;L&#7847n &#273&#7847u ti&ecirc;n ph&aacute;t hi&#7879n &#273&#432&#7907c nhi&#7873u h&#7907p ch&#7845t m&#7899i c&oacute; ho&#7841t t&iacute;nh ch&#7889ng ung th&#432</span></strong></span></span></div> <div><span style="font-size: small; "><span style="font-family: Arial; "><br /> </span></span></div> <div style="text-align: justify; "><span style="font-size: small; "><span style="font-family: Arial; ">L&#7847n &#273&#7847u ti&ecirc;n c&aacute;c nh&agrave; khoa h&#7885c Vi&#7879t Nam &#273&atilde; ph&aacute;t hi&#7879n &#273&#432&#7907c h&agrave;ng tr&#259m h&#7907p ch&#7845t, trong &#273&oacute; c&oacute; nh&#7919ng h&#7907p ch&#7845t m&#7899i, &#273&#432&#7907c &#273&aacute;nh gi&aacute; c&oacute; ho&#7841t t&iacute;nh ch&#7889ng ung th&#432, kh&aacute;ng sinh. &#272&acirc;y l&agrave; nh&#7919ng nguy&ecirc;n li&#7879u ph&#7909c v&#7909 cho c&aacute;c nghi&ecirc;n c&#7913u s&acirc;u v&#7873 d&#432&#7907c l&yacute; nh&#7857m t&#7841o ra c&aacute;c s&#7843n ph&#7849m c&#7909 th&#7875 &#273i&#7873u tr&#7883 nh&#7919ng b&#7879nh hi&#7875m ngh&egrave;o t&#7915 ch&iacute;nh c&aacute;c c&acirc;y, con tr&ecirc;n bi&#7875n.</span></span></div> <div style="text-align: center; ">&nbsp;</div> <div style="text-align: center; "><img width="192" height="147" alt="" src="300_sac20ky20hieu20long.jpg" /></div> <div style="text-align: center; ">&nbsp;</div> <div style="text-align: justify; "><span style="font-size: small; "><span style="font-family: Arial; ">Nghi&ecirc;n c&#7913u n&agrave;y &#273&#432&#7907c tri&ecirc;&#777n khai trong c&#7909m c&ocirc;ng tr&igrave;nh &ldquo;Khai th&aacute;c s&#7917 d&#7909ng h&#7907p l&yacute; ngu&#7891n t&agrave;i nguy&ecirc;n thi&ecirc;n nhi&ecirc;n sinh v&#7853t Bi&#7875n Vi&#7879t Nam nh&#7857m t&#7841o ra c&aacute;c s&#7843n ph&#7849m c&oacute; gi&aacute; tr&#7883 ph&#7909c v&#7909 cu&#7897c s&#7889ng&rdquo; do c&aacute;c nh&agrave; khoa h&#7885c thu&#7897c Vi&#7879n KHCNVN (g&#7891m c&aacute;c Vi&#7879n H&oacute;a sinh bi&#7875n, Vi&#7879n H&oacute;a h&#7885c c&aacute;c H&#7907p ch&#7845t thi&ecirc;n nhi&ecirc;n, Vi&#7879n Nghi&ecirc;n c&#7913u v&agrave; &#7912ng d&#7909ng c&ocirc;ng ngh&#7879 Nha trang, Vi&#7879n T&agrave;i nguy&ecirc;n M&ocirc;i tr&#432&#7901ng Bi&#7875n) th&#7921c hi&#7879n. C&ocirc;ng tr&igrave;nh vinh d&#7921 &#273&#432&#7907c trao gi&#7843i th&#432&#7903ng Nh&agrave; n&#432&#7899c v&#7873 Khoa h&#7885c c&ocirc;ng ngh&#7879 n&#259m 2010.</span></span></div> <div style="text-align: justify; ">&nbsp;</div> <div style="text-align: justify; "><span style="font-size: small; "><span style="font-family: Arial; ">TS Nguy&#7877n Ho&agrave;i Nam, Ph&oacute; Vi&#7879n tr&#432&#7903ng Vi&#7879n H&oacute;a sinh bi&#7875n, Vi&#7879n KHCNVN, th&agrave;nh vi&ecirc;n c&#7911a c&#7909m c&ocirc;ng tr&igrave;nh cho bi&#7871t, c&ocirc;ng tr&igrave;nh cung c&#7845p b&#7897 t&#432 li&#7879u t&#7893ng qu&aacute;t v&#7873 c&aacute;c nh&oacute;m d&#432&#7907c li&#7879u, khu v&#7921c ch&#7913a d&#432&#7907c li&#7879u, c&aacute;c quy tr&igrave;nh chi&#7871t xu&#7845t ho&#7841t ch&#7845t (d&#7841ng s&aacute;ng ch&#7871), c&aacute;c s&#7889 li&#7879u v&#7873 ho&#7841t t&iacute;nh sinh h&#7885c c&#7911a c&aacute;c m&#7851u, c&aacute;c h&#7907p ch&#7845t m&#7899i v&agrave; c&aacute;c h&#7907p ch&#7845t c&oacute; ho&#7841t t&iacute;nh sinh h&#7885c.</span></span><span style="font-size: small; "><span style="font-family: Arial; "> B&ocirc;&#803 d&#7919 li&#7879u c&#7911a C&ocirc;ng tr&igrave;nh g&#7891m 52 c&ocirc;ng tr&igrave;nh &#273&#432&#7907c c&ocirc;ng b&#7889 trong &#273&oacute; c&oacute; 2 b&#7857ng &#273&#7897c quy&#7873n s&aacute;ng ch&#7871, 22 c&ocirc;ng tr&igrave;nh c&ocirc;ng b&#7889 tr&ecirc;n t&#7841p ch&iacute; qu&#7889c t&#7871 c&oacute; uy t&iacute;n, 03 s&aacute;ch chuy&ecirc;n kh&#7843o, 25 c&ocirc;ng tr&igrave;nh c&ocirc;ng b&#7889 tr&ecirc;n t&#7841p ch&iacute; chuy&ecirc;n ng&agrave;nh trong n&#432&#7899c. &#272&acirc;y l&agrave; b&#7897 t&#432 li&#7879u qu&yacute; ph&#7909c v&#7909 &#273&agrave;o t&#7841o c&aacute;n b&#7897 tr&#7867 trong l&#297nh v&#7921c H&oacute;a h&#7907p ch&#7845t thi&ecirc;n nhi&ecirc;n bi&#7875n g&oacute;p ph&#7847n n&acirc;ng cao tr&igrave;nh &#273&#7897 nghi&ecirc;n c&#7913u bi&#7875n &#7903 Vi&#7879t Nam l&ecirc;n t&#7847m qu&#7889c t&#7871.</span></span></div> <div style="text-align: justify; ">&nbsp;</div> <div style="text-align: justify; "><span style="font-size: small; "><span style="font-family: Arial; ">&#272&aacute;ng ch&uacute; &yacute; l&agrave; vi&ecirc;&#803c nghi&ecirc;n c&#7913u, ph&aacute;t hi&#7879n ra h&agrave;ng tr&#259m h&#7907p ch&#7845t c&oacute; ho&#7841t t&iacute;nh ch&ocirc;&#769ng ung th&#432, kh&aacute;ng sinh r&acirc;&#769t cao, trong &#273&oacute; c&oacute; nh&#7919ng h&#7907p ch&#7845t m&#7899i l&#7847n &#273&#7847u ti&ecirc;n &#273&#432&#7907c ph&aacute;t hi&#7879n &#273&oacute;ng g&oacute;p r&#7845t l&#7899n v&agrave;o kho t&agrave;ng h&#7907p ch&#7845t thi&ecirc;n nhi&ecirc;n bi&#7875n tr&ecirc;n th&#7871 gi&#7899i, &#273&ocirc;&#768ng th&#7901i g&oacute;p ph&#7847n qu&#7843ng b&aacute; v&agrave; &#273&#432a c&aacute;c th&ocirc;ng tin v&#7873 nghi&ecirc;n c&#7913u bi&#7875n Vi&#7879t Nam v&#432&#417n ra qu&#7889c t&#7871. Trong h&#417n 4 n&#259m nghi&ecirc;n c&#7913u, v&#7899i 405 m&#7851u sinh v&#7853t bi&#7875n &#273&#432&#7907c thu th&#7853p, c&aacute;c nh&agrave; khoa h&#7885c &#273&atilde; ti&#7871n h&agrave;nh s&agrave;ng l&#7885c ho&#7841t t&iacute;nh sinh h&#7885c c&#7911a m&#7897t s&#7889 lo&agrave;i h&#7843i mi&ecirc;n, h&#7843i s&acirc;m v&agrave; nghi&ecirc;n c&#7913u s&acirc;u v&#7873 th&agrave;nh ph&#7847n h&oacute;a h&#7885c c&aacute;c h&#7907p ch&#7845t c&#7911a m&#7897t s&#7889 lo&agrave;i c&oacute; tri&#7875n v&#7885ng theo &#273&#7883nh c&aacute;c h&#432&#7899ng ch&#7889ng ung th&#432 v&agrave; kh&aacute;ng sinh. Th&iacute; nghi&#7879m invitro ho&#7841t t&iacute;nh sinh h&#7885c c&#7911a 247/405 m&#7851u sinh v&#7853t bi&#7875n c&oacute; c&aacute;c ho&#7841t t&iacute;nh kh&aacute;ng sinh, ch&#7889ng ung th&#432. Nghi&ecirc;n c&#7913u h&oacute;a h&#7885c theo &#273&#7883nh h&#432&#7899ng ho&#7841t t&iacute;nh sinh h&#7885c c&#7911a 5 &#273&#7889i t&#432&#7907ng sinh v&#7853t bi&#7875n ch&#7885n l&#7885c (g&#7891m: h&#7843i mi&ecirc;n c&agrave;nh Haliclona sp, b&#7885t bi&#7875n x&#7889p &#273en Icrinia echinata, c&#7847u gai Diadema setosum, h&#7843i s&acirc;m Holothuria vagabunda v&agrave; Holothuria scabra); &#273&atilde; t&aacute;ch chi&#7871t x&aacute;c &#273&#7883nh c&#7845u tr&uacute;c 30 ch&#7845t s&#7841ch (trong &#273&oacute; 4 ch&#7845t m&#7899i l&#7847n &#273&#7847u ti&ecirc;n &#273&#432&#7907c ph&acirc;n l&#7853p t&#7915 thi&ecirc;n nhi&ecirc;n) c&ugrave;ng nh&#7919ng k&#7871t qu&#7843 th&#7917 nghi&#7879m ho&#7841t t&iacute;nh sinh h&#7885c cho th&#7845y m&#7897t s&#7889 ch&#7845t s&#7841ch c&oacute; ho&#7841t t&iacute;nh ch&#7889ng ung th&#432 v&agrave; kh&aacute;ng sinh r&#7845t cao.</span></span></div> <div style="text-align: justify; ">&nbsp;</div> <div style="text-align: justify; "><span style="font-size: small; "><span style="font-family: Arial; ">Tr&ecirc;n c&#417 s&#7903 ph&aacute;t hi&#7879n c&aacute;c d&#432&#7907c li&#7879u bi&#7875n qu&yacute;, c&aacute;c nh&agrave; khoa h&#7885c &#273&atilde; x&acirc;y d&#7921ng &#273&#432&#7907c quy tr&igrave;nh chi&#7871t xu&#7845t c&aacute;c ho&#7841t ch&#7845t c&oacute; kh&#7843 n&#259ng &#7913c ch&#7871 s&#7921 ph&aacute;t tri&#7875n c&#7911a m&#7897t s&#7889 d&ograve;ng t&#7871 b&agrave;o ung th&#432 ng&#432&#7901i nh&#432 ung th&#432 v&uacute;, ung th&#432 v&ograve;m h&#7885ng, ung th&#432 c&#7893 t&#7917 cung&hellip; K&ecirc;&#769t qu&#7843 n&agrave;y g&oacute;p ph&acirc;&#768n h&igrave;nh th&agrave;nh c&aacute;c nguy&ecirc;n li&#7879u cho c&aacute;c nghi&ecirc;n c&#7913u s&acirc;u h&#417n v&#7873 d&#432&#7907c l&yacute; nh&#7857m cho ra c&aacute;c thu&#7889c &#273i&#7873u tr&#7883 ung th&#432 ph&#7909c v&#7909 cho nh&#7919ng ng&#432&#7901i kh&ocirc;ng may b&#7883 m&#7855c c&#259n b&#7879nh hi&#7875m ngh&egrave;o n&agrave;y.</span></span></div> <div style="text-align: justify; ">&nbsp;</div> <div style="text-align: justify; "><span style="font-size: small; "><span style="font-family: Arial; ">Ch&iacute;nh c&aacute;c k&ecirc;&#769t qu&#7843 nghi&ecirc;n c&#7913u v&agrave; &#273&agrave;o t&#7841o c&aacute;n b&ocirc;&#803 h&#7879 th&#7889ng, b&agrave;i b&#7843n c&#7911a c&#7909m c&ocirc;ng tr&igrave;nh &ldquo;Khai th&aacute;c s&#7917 d&#7909ng h&#7907p l&yacute; ngu&ocirc;&#768n t&agrave;i nguy&ecirc;n thi&ecirc;n nhi&ecirc;n sinh v&acirc;&#803t bi&ecirc;&#777n Vi&ecirc;&#803t Nam nh&#7857m t&#7841o ra c&aacute;c s&#7843n ph&acirc;&#777m c&oacute; gi&aacute; tr&#7883 ph&#7909c v&#7909 cu&ocirc;&#803c s&ocirc;&#769ng&rdquo; &#273&atilde; g&oacute;p ph&#7847n th&uacute;c &#273&#7849y v&agrave; ph&aacute;t tri&#7875n h&#432&#7899ng nghi&ecirc;n c&#7913u v&#7873 h&oacute;a sinh bi&#7875n &#7903 Vi&#7879t Nam. Vi&ecirc;&#803n H&oacute;a sinh bi&ecirc;&#777n v&#7899i ch&#7913c n&#259ng Vi&#7879n nghi&ecirc;n c&#7913u c&#7845p qu&#7889c nghi&ecirc;n c&#7913u c&#417 b&#7843n v&agrave; &#7913ng d&#7909ng v&#7873 h&oacute;a sinh bi&#7875n &#273&atilde; &#273&#432&#7907c th&agrave;nh l&#7853p theo Quy&#7871t &#273&#7883nh s&#7889 470/Q&#272-TTg ng&agrave;y 12/4/2010 c&#7911a Th&#7911 t&#432&#7903ng Ch&iacute;nh ph&#7911. Ngo&agrave;i ra, B&#7897 Khoa h&#7885c v&agrave; C&ocirc;ng ngh&#7879 c&#361ng &#273&atilde; x&aacute;c &#273&#7883nh h&#432&#7899ng nghi&ecirc;n c&#7913u c&aacute;c ho&#7841t ch&#7845t sinh h&#7885c bi&#7875n l&agrave; m&#7897t trong c&aacute;c h&#432&#7899ng tr&#7885ng t&acirc;m trong Ch&#432&#417ng tr&igrave;nh &ldquo;Nghi&ecirc;n c&#7913u c&#417 b&#7843n &#273&#7883nh h&#432&#7899ng &#7913ng d&#7909ng giai &#273o&#7841n 2011-2015&rdquo; c&#7911a Nh&agrave; n&#432&#7899c. &#272&acirc;y l&agrave; nh&#7919ng c&#417 s&#7903 b&#432&#7899c &#273&acirc;&#768u &#273&ecirc;&#777 vi&ecirc;&#803c khai th&aacute;c ngu&ocirc;&#768n d&#432&#7907c li&ecirc;&#803u bi&ecirc;&#777n Vi&ecirc;&#803t Nam &#273&#432a ra &#273&#432&#7907c nh&#7919ng s&#7843n ph&acirc;&#777m ph&#7909c v&#7909 ch&#259m s&oacute;c s&#7913c kh&#7887e c&ocirc;&#803ng &#273&ocirc;&#768ng.</span></span></div> <div style="text-align: justify; ">&nbsp;</div> <div style="text-align: justify; "><span style="font-size: small; "><span style="font-family: Arial; ">M&ocirc;&#803t s&ocirc;&#769 s&#7843n ph&#7849m n&ocirc;&#777i b&acirc;&#803t c&#7911a C&#7909m c&ocirc;ng tr&igrave;nh &quot;Khai th&aacute;c s&#7917 d&#7909ng h&#7907p l&yacute; ngu&ocirc;&#768n t&agrave;i nguy&ecirc;n thi&ecirc;n nhi&ecirc;n sinh v&acirc;&#803t bi&ecirc;&#777n Vi&ecirc;&#803t Nam nh&#7857m t&#7841o ra c&aacute;c s&#7843n ph&acirc;&#777m c&oacute; gi&aacute; tr&#7883 ph&#7909c v&#7909 cu&ocirc;&#803c s&ocirc;&#769ng&quot;:</span></span></div> <div style="text-align: justify; ">&nbsp;</div> <div style="text-align: justify; "><span style="font-size: small; "><span style="font-family: Arial; ">1. Th&#7921c ph&#7849m ch&#7913c n&#259ng CEFISH (6585/2007/YT &ndash; CNTC) t&#7915 c&aacute; bi&ecirc;&#777n, b&ocirc;&#777 sung Omega-3 c&#7843i thi&ecirc;&#803n ch&#7913c n&#259ng chuy&ecirc;&#777n h&oacute;a lipit m&aacute;u, huy&ecirc;&#769t &aacute;p &#7903 b&ecirc;&#803nh nh&acirc;n tim m&#7841ch;</span></span></div> <div style="text-align: justify; ">&nbsp;</div> <div style="text-align: justify; "><span style="font-size: small; "><span style="font-family: Arial; ">2. Th&#7921c ph&acirc;&#777m ch&#7913c n&#259ng vi&ecirc;n t&#259ng l&#7921c BIONAMINE (956/2008/YT-CNTC) t&#7915 sao bi&#7875n, gi&uacute;p t&#259ng c&#432&#7901ng th&ecirc;&#777 l&#7921c cho v&acirc;&#803n &#273&ocirc;&#803ng vi&ecirc;n;</span></span></div> <div style="text-align: justify; ">&nbsp;</div> <div style="text-align: justify; "><span style="font-size: small; "><span style="font-family: Arial; ">3. Th&#7921c ph&acirc;&#777m ch&#7913c n&#259ng vi&ecirc;n nang m&ecirc;&#768m B&agrave;o ng&#432 HALIOTIS (6714/2007/YT-CNTC) t&#7915 b&agrave;o ng&#432, gi&uacute;p b&ocirc;&#768i b&ocirc;&#777 c&#417 th&ecirc;&#777</span></span></div> <div style="text-align: justify; ">&nbsp;</div> <div style="text-align: justify; "><span style="font-size: small; "><span style="font-family: Arial; ">4. Th&#7921c ph&acirc;&#777m ch&#7913c n&#259ng vi&ecirc;n nang m&ecirc;&#768m HASAMIN (4978/2006/YT-CNTC) t&#7915 h&#7843i s&acirc;m, gi&uacute;p t&#259ng c&#432&#7901ng sinh l&#7921c;</span></span></div> <div style="text-align: justify; ">&nbsp;</div> <div style="text-align: justify; "><span style="font-size: small; "><span style="font-family: Arial; ">5. Th&#7921c ph&acirc;&#777m ch&#7913c n&#259ng SEAVIE (4381/2008/YT-CNTC) t&#7915 san h&ocirc; m&#7873m, gi&uacute;p ch&ocirc;&#769ng lo&atilde;ng x&#432&#417ng, ch&ocirc;&#769ng tho&aacute;i h&oacute;a kh&#7899p;</span></span></div> <div style="text-align: justify; ">&nbsp;</div> <div style="text-align: justify; "><span style="font-size: small; "><span style="font-family: Arial; ">6. Th&#7921c ph&acirc;&#777m ch&#7913c n&#259ng FUCOIDAN (2455/2010/YT-CNTC) t&#7915 rong bi&#7875n gi&uacute;p ph&ograve;ng ng&#7915a b&ecirc;&#803nh vi&ecirc;m lo&eacute;t d&#7841 d&agrave;y v&agrave; ung th&#432</span></span></div> <div style="text-align: justify; ">&nbsp;</div> <div style="text-align: justify; "><span style="font-size: small; "><span style="font-family: Arial; ">7. C&#7889t tho&aacute;i v&#432&#417ng (6126/2008/YT-CNTC) v&#7899i th&agrave;nh ph&acirc;&#768n c&oacute; ch&#7913a d&acirc;&#768u V&#7865m xanh, h&ocirc;&#771 tr&#7907 &#273i&ecirc;&#768u tr&#7883 tho&aacute;i h&oacute;a c&ocirc;&#803t s&ocirc;&#769ng, gai &#273&ocirc;i c&ocirc;&#803t s&ocirc;&#769ng, tho&aacute;t v&#7883 &#273&#297a &#273&ecirc;&#803m...</span></span></div> <div style="text-align: justify; "><font face="Arial" size="2"><br /> </font></div> <div style="text-align: justify; "> <p class="MsoNormal" style="line-height: 12.25pt; background-image: initial; background-attachment: initial; background-origin: initial; background-clip: initial; background-color: white; background-position: initial initial; background-repeat: initial initial; "><span style="color: rgb(0, 0, 0); "><span style="font-size: small; "><span style="font-family: Arial; ">* GS.TS Ch&acirc;u V&#259n Minh, Ch&#7911 t&#7883ch Vi&#7879n KHCNVN, Ch&#7911 nhi&#7879m &#273&#7873 t&agrave;i t&#7915ng chia s&#7867, &#7903 n&#432&#7899c ta, c&oacute; b&#7901 bi&#7875n d&agrave;i h&#417n 3.260km v&agrave; v&ugrave;ng th&#7873m l&#7909c &#273&#7883a r&#7897ng kho&#7843ng 1 tri&#7879u km<sup>2</sup> l&agrave; khu v&#7921c ch&#7913a &#273&#7921ng nhi&#7873u lo&agrave;i sinh v&#7853t bi&#7875n. Trong s&#7889 &#273&oacute;, nh&oacute;m sinh v&#7853t c&oacute; &#273&#7897c t&#7889 (nh&#432 c&aacute; n&oacute;c, r&#7855n bi&#7875n, xoang tr&agrave;ng...) ho&#7863c c&oacute; ch&#7913a c&aacute;c ch&#7845t ho&#7841t t&iacute;nh sinh h&#7885c ti&#7873m n&#259ng (nh&#432 h&#7843i mi&ecirc;n, san h&ocirc; m&#7873m...) r&#7845t phong ph&uacute;. Tuy nhi&ecirc;n, t&#7915 tr&#432&#7899c &#273&#7871n nay, trong ph&aacute;t tri&#7875n kinh t&#7871 bi&#7875n, ch&uacute;ng ta ch&#7911 y&#7871u ch&#7881 quan t&acirc;m t&#7899i nh&#7919ng lo&agrave;i sinh v&#7853t bi&#7875n c&oacute; gi&aacute; tr&#7883 th&#7921c ph&#7849m ho&#7863c xu&#7845t kh&#7849u. &Iacute;t quan t&acirc;m t&#7899i gi&aacute; tr&#7883 cung c&#7845p d&#432&#7907c li&#7879u v&agrave; c&aacute;c ch&#7845t c&oacute; ho&#7841t t&iacute;nh sinh h&#7885c cao cho ng&agrave;nh h&oacute;a d&#432&#7907c.</span></span></span><span style="font-size:8.0pt;font-family:Arial;color:#444444"><o:p></o:p></span></p> </div> <div style="text-align: justify; "><span style="font-size: small; "><span style="font-family: Arial; "><br type="_moz" /> </span></span></div> <div style="text-align: right; "><span style="font-size: small; "><span style="font-family: Arial; "><strong>B&iacute;ch Di&ecirc;&#803p, Vi&#7879n KHVNVN</strong></span></span></div> <div style="text-align: right; "><span style="font-size: small; "><span style="font-family: Arial; "> <em>Ngu&ocirc;&#768n: TS Nguy&ecirc;&#771n Ho&agrave;i Nam , Vi&ecirc;&#803n H&oacute;a sinh bi&ecirc;&#777n</em></span></span></div> <div style="text-align: right; ">&nbsp;</div> </meta> </div> </html>

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